Guidance on the use of acidic electrolytic water/ hypochlorite for the prevention of COVID

Guidance on the use of acidic electrolytic water/ hypochlorite for the prevention of COVID

Two of the most important aspects of COVID prevention are wearing a mask and disinfection. Hypochlorous acid is a new type of chlorine disinfectant that can eliminate COVID.
The following is an introduction to the characteristics and use of acidic electrolytic water/ hypochlorite water (the main ingredient is hypochlorous acid).

Introduction to acidic electrolytic water/ hypochlorite:

Ⅰ, Acidic electrolyzed water
Acidic electrolyzed water (pH <7) is produced by electrolysis of aqueous sodium chloride and/or hydrochloric acid in a diaphragm or diaphragmless electrolytic bath, with hypochlorous acid as the main bactericidal component. Among them, acidic oxidation potential water (strong acidic electrolyzed water) pH 2.0-3.0, slightly acidic electrolyzed water pH 5.0-6.5.

Ⅱ, hypochlorous acid disinfectant with hypochlorous acid
Ⅱ-1，Disinfectant containing stable hypochlorous acid in the disinfectant stock solution.
The main functional component of both acidic electrolytic water/hypochlorinated water is hypochlorous acid. Hypochlorous acid can be produced by electrolysis of dilute hydrochloric acid, sodium chloride solutions, or by acidifying sodium hypochlorite with hydrochloric acid. The form of chlorine in water is pH dependent and at pH 5.0 - 6.5 it is mainly in the form of hypochlorous acid, so hypochlorous acid can be produced by mixing a low concentration solution of sodium hypochlorite with hydrochloric acid (or acetic acid, citric acid etc.) to adjust the pH. Alternatively, hypochlorite can be produced by electrolysis of low concentrations of aqueous solutions of hydrochloric acid and/or sodium chloride using diaphragm or diaphragmless electrolysers.

II-2,  In biological systems, hypochlorous acid (HClO) is produced by the oxidation of chloride ions by the combined action of neutrophil-derived myeloperoxidase and hydrogen peroxide. Quantitative analysis shows that 100,000 activated neutrophils can produce approximately 2 x 10-7 mol of hypochlorous acid during a 2h incubation time.

III, Hypochlorous acid inactivation capacity
III-1,  Hypochlorous acid has a good inactivation effect on viruses. Studies have shown that poliovirus can be effectively inactivated by using 250 mg/L hypochlorous acid for 10 min on poliovirus prepared according to the Technical Specification for Disinfection.

III-2,  in addition, experiments have shown that hypochlorous acid can produce an effective killing effect on viruses under the conditions of flushing and gasification. The test of Kim H et al. selected human influenza A virus as the test object, and the use of 3.5 mg/L hypochlorous acid was used at room temperature for 30s, and the test results showed that the logarithmic killing value of human influenza A virus was 3.2 virus (H7N1) inactivation effect, and the test results showed that hypochlorous acid could reduce the virus titer in the absence of organic matter, regardless of direct spray or indirect spray. In the presence of organic matter, hypochlorous acid loses its virucidal activity.

The results of Hughson AG et al. show that HClO can block the self-proliferative activity of prions and other amyloids, and these test results suggest that hypochlorous acid has an effective killing effect on viruses